Associations between Tumor Necrosis Factor-Alpha Polymorphisms and the Risk of Tuberculosis: A Meta-Analysis

Background: Tuberculosis (TB) is a global infectious disease that seriously threatens human health, but the association between tumor necrosis factor-alpha (TNF-α, TNF) gene and TB remains controversial. Methods: Relevant studies published in English or Chinese up to April 12, 2019, were searched from PubMed, Embase, Metstr, Web of Science, Medline, and CNKI databases. The associations were estimated by Odds Ratios (ORs) and 95% Confidence Intervals (CIs).