Mitochondria and Aged Women Egg

Since the first “test-tube baby” named Louise Joy Brown was born in 1978 [1,2], human in vitro fertilization (IVF) has become widely accepted by infertile couples for fertility treatments. There are more than 0.2 million babies born every year and a cumulative total of 6.5 million IVF babies have been born worldwide [3,4]. Moreover, the average pregnancy rate (PR) in overall cycles has significantly increased from 11.1%