SF Journal of Pharmaceutical and Analytical Chemistry
SFJPAC

Determination of Sugammadex in Human Plasma using Protein Precipitation and Ultra High Performance Liquid Chromatography/Tandem Mass Spectrometry

Research Article Volume 1 Issue 1
Zeng W*, Xu Y, Constanzer ML, Goykhman D and Woolf EJ
Corresponding Author: Zeng W

Abstract

A simple LC-MS/MS method for the quantification of sugammadex in human plasma is described. Samples were prepared using protein precipitation with acetonitrile containing 0.37% hydrochloric acid as precipitator and Waters Ostra plate for protein and phospholipid removal.

Article Information

Journal SF Journal of Pharmaceutical and Analytical Chemistry
Article Type Research Article
Volume 1
Issue 1